Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases

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Neurodegenerative diseases lead to a progressive loss of neurons, resulting in severe symptoms like dementia and motor dysfunction. The book explores two main types of cell death involved in this process: necrosis and apoptosis. Necrosis is characterized by passive cell swelling and significant mitochondrial damage, causing inflammatory responses. In contrast, apoptosis is an active process involving caspases, leading to cell shrinkage and chromatin condensation. The text delves into the mechanisms of these cell death types and their implications for neurodegenerative conditions.