The Ichthyoses

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This book deals with those inherited scaling disorders which by convention are called the "ichthyoses". Today, more than 20 different types are known, and because of clinical similarities differential diagnosis of these conditions is often difficult. For the first time all of these disorders, including many uncommon types, are presented with their clinical features, genetic aspects, histological and biochemical findings in a single comprehensive volume. A new clinically oriented classification provides easy access to the correct diagnosis; it has far-reaching consequences for genetic counseling and may influence many decisions an informed patient will want to take. Problems relating to prenatal diagnosis are discussed for each of these disorders. Topical and systemic treatment modalities are covered in special chapters and reflect the personal experience of the author during an involvement of ten years with ichthyosis patients. The book is primarily aimed at physicians caring for ichthyosis patients. However, the latest achievements made in the fields of lipid chemistry, enzymology, and molecular genetics are incorporated as they relate to the various disorders. Therefore, this volume will also be of interest to researchers involved in skin biology or human genetics.