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Principles of Process Research and Chemical Development in the Pharmaceutical Industry

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This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.

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Principles of Process Research and Chemical Development in the Pharmaceutical Industry, Oljan Repic

Sprache
Erscheinungsdatum
1998
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(Hardcover)
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Titel
Principles of Process Research and Chemical Development in the Pharmaceutical Industry
Sprache
Englisch
Autor*innen
Oljan Repic
Erscheinungsdatum
1998
Einband
Hardcover
Seitenzahl
273
ISBN10
0471165166
ISBN13
9780471165163
Reihe
Beschreibung
This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.