Rodolfo Paoletti Bücher

Vitamin C, or ascorbic acid, has a long and multifaceted scientific history. In 1937, the Nobel Prize for Physiology and Medicine was awarded to Albert Szent-Gyorgyi'in recognition of his discoveries concerning the biological oxida­ tion processes with special reference to vitamin C', and the Nobel Prize for Chemistry was shared by Sir Norman W. Haworth, who was the first to synthesize the vitamin. Vitamin C is a potent antioxidant, and this action represented the theoretical basis for various lines of investigation on this molecule in which the potential role of ascorbic acid in the prevention and treatment of a series of dis­ eases, whose pathogenesis is linked to an excess of free radicals such as athero­ sclerosis and cancer, have been examined. These data have been analyzed in detail by experts in biochemistry, epidemi­ ology, and preventive and clinical medicine in the International Symposium Vitamin C, the state of the art in disease prevention sixty years after the Nobel Prize, held in Monte Carlo from October 31 to November 1, 1997, under the aus­ pices and the scientific endorsement of the Nutrition Foundation of Italy and with the financial support of Bracco SpA and Merck.

The book delves into the complexities of the circulatory system, emphasizing that blood vessels, particularly arteries, are dynamic organs rather than mere conduits. It explores how their structure varies with location and age, and how specific arteries are predisposed to certain diseases based on experimental and pathological evidence. The metabolic activity of arterial walls, their response to stimuli, and the impact of circulating blood on their morphology and function are key themes, highlighting the intricate relationship between blood vessels and overall cardiovascular health.

1 Chocolate as Medicine: A Changing Framework of Evidence Throughout History (P.K. Wilson) 2 Industrial Treatment of Cocoa in Chocolate Production: Health Implications (H. Bernaert) 3 Biomarkers of Cocoa Consumption (N. Khan) 4 Botany and Pharmacognosy of the Cacao Tree (M. L. Colombo) 5... číst celé

This volume represents the proceedings ofthe invited lectures ofthe first International Symposium on "Serotonin from Cell Biology to Pharmacology and Therapeutics" which was held in Florence on March 29 -Aprill, 1989. This meeting, held under the co-sponsorship of the Serotonin Club and the Fondazione Giovanni Lorenzini, represents the first attempt to bring together scientists fascinated by the complexity of the action of 5-hydroxytryptamine throughout the body and in various species. Hence this volume provides the reader with the unique overview of the sources, effects, receptors, physiological actions and pathological role of Serotonin. As such it will be of interest not only to the person devoting herorhis research efforts to the study of 5-hydroxytryptamine but also to all scholars and even clinicians wanting to know how the powerful monoamine can modulate cellular functions. To accelerate the publication of these proceedings the Editors and the publishers have selected the camera ready format and have avoided a lengthy refereeing process. Hence the scientific content of, and the opinions expressed in the chapters are the sole responsibility of the authors. The Editors Milan and Houston The Editors want to thank Mrs. H. Liepman and her staff at Kluwer for the prompt and efficient handling of the manuscripts.

(Symp. Vienna 5/90) Insulin regulation; sex hormone control of triglyceride metabolism; the Framingham study.