Felix Franks Bücher

Focusing on ion-solvent effects, this volume addresses the complexities of simple ionic solutions, distinguishing itself from broader texts on electrolyte solutions. It reflects on the evolution of classical theories by Debye, Huckel, Onsager, and Fuoss, questioning the point at which a theory achieves "classical" status. The author highlights the limitations of established theories, particularly as new molecular and thermodynamic insights challenge fundamental assumptions, suggesting a need for re-evaluation in light of modern research techniques.

Exploring various chemical interactions, this book delves into hydrophobic interactions and their significance in surfactants, dyestuffs, lipids, nucleic acids, peptides, proteins, and polysaccharides. It also examines synthetic polymers, providing insights into their structures and functions. Each section highlights the unique properties and applications of these substances, making it a comprehensive resource for understanding complex biochemical interactions and materials science.

This collection features critical reviews on water science, drawing from the extensive research previously published in the comprehensive series "Water - A Comprehensive Treatise." Each review delves into various aspects of water science, providing in-depth analysis and insights that contribute to the understanding of this vital resource. The work serves as a valuable resource for researchers and professionals in the field, highlighting contemporary issues and advancements in water science.

Focusing on complex aqueous systems, this final volume of the series explores advanced topics in water's role within disperse systems, diverging from earlier theoretical frameworks. It addresses significant applications in various fields, such as food processing, cryopreservation, and hemodynamics, emphasizing the critical interactions involving water. The text aims to enhance understanding of these complex systems, reflecting on the evolution of water science since the series' inception and its relevance to contemporary research and industry challenges.

Focusing on the adoption of freeze-drying in the pharmaceutical sector, this book offers a comprehensive exploration of the process, from historical context to modern applications. It details the scientific principles behind freezing and drying, formulation development, and product attributes. Key topics include the engineering of scaling up processes and the economics involved. The text also presents case studies and discusses future advancements in drying methods. Aimed at professionals and academics, it serves as a valuable resource for understanding this critical technology in biopharmaceuticals.

Recent advancements in physical and life sciences highlight the critical role of water, prompting the release of this new volume despite previous claims of concluding the series. It explores the impact of X-ray and neutron scattering techniques on understanding aqueous solutions and protein structures. Additionally, it provides a timely review of ab initio methods for small molecule hydration and conformational studies. The volume also addresses solvent effects in reaction kinetics, which were previously overlooked, reflecting significant progress made since 1972 in the chemistry of mixed aqueous solvents.

Felix Franks' new volume, Protein Biotechnology, is a comprehensive compendium of state-of-the-art techniques for isolating, purifying, characterizing, and analyzing proteins as commercial products, both in vitro and in vivo. The book also highlights leading-edge analytical methods used throughout biotechnology today, especially in quality control, and contains a wealth of economic and technical information. The book's particular strength lies in its emphasis on proteins as commercial products, not merely experimental laboratory entities. Topics treated include: description and classification of proteins economics and technology of characterization analytical chromatography of amino acids, peptides, and proteins structure, organization, and function posttranslational processing fragmentation peptide sequence determination electrophoretic techniques polyclonal and monoclonal antibodies conformational stability protein hydration recombinant protein technology storage stabilization process purification. An essential tool for everyone who needs to stay effective in today's highly competitive biotechnology arena.