Digital Pathology

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This special topic issue covers the essential elements of digital pathology. The basic components of a whole slide imaging system (WSI) are reviewed, and interoperability and standards recommendations are offered, including a thorough revision of the international guidelines on digital pathology. Further, the publication provides a study on conventional microscopy versus WSI in pre-graduate and post-graduate medical training. It includes a study on synoptic pathology reports, evidence supporting the use of WSI for primary diagnosis in the different pathology subspecialties, second opinion telepathology, and practical recommendations for large volume storage. New technologies that lead to future 3D representation of tissue histology are examined. Finally, this issue discusses integrative digital pathology, micro-semiology, comprehensive immunohistochemistry, and computational pathology concepts. Digital Pathology is primarily aimed at pathologists, residents, technicians, biologists, and IT scientists. It provides answers to current challenges and some innovative proposals for the future.