Direct analysis in real time mass spectrometry

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Clear, comprehensive, and state-of-the-art, this groundbreaking book delves into the emerging technology of direct analysis in real time mass spectrometry, authored by a noted expert in the field. It reviews the background and recent developments in DART-MS, a technique invented in 2005 that addresses various analytical challenges across multiple environments, including food science, forensics, and clinical analysis. The text introduces the technology's history and theoretical background, particularly the ionization mechanism. It includes chapters on sampling and the coupling of DART to different mass spectrometers, followed by an extensive discussion of diverse applications. Notably, DART requires no laborious sample preparation, as ionization occurs directly on the sample surface, making it particularly appealing for forensic and food science applications. This vital text sets the standard for this important ionization technique, thoroughly discussing instrumentation, applications, and addressing challenges and disadvantages. It serves as an essential resource for academics, analytical chemists, pharmaceutical chemists, clinical chemists, forensic scientists, and others seeking to understand the latest advancements in the field.