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The point of departure of the oeuvre of Anne-Mie Van Kerckhoven is the human brain with its analytical and irrational potential in terms of perception and cognizance. Van Kerckhoven’s logic is consistently counteracted by absurdity or mental disruptions, and the analytical is joined with the mystical without viewing this as a contradiction. Van Kerckhoven began dealing with research on artificial intelligence early on, whereby visual languages dominated that are influenced by scientific imaging processes: diagrams, graphic animations, and text-image schemes. She used digital on par with analog forms of expression as early as the 1980s and transferred the digitally constructed worlds into space. The artist uses primarily female bodies like “selfies” as protagonists in drawings, paintings, prints, and films. What is characteristic about her oeuvre is her biographical beginning in the counterculture of punk, feminism, and in the anti-academism typical of her generation, which engendered a pop aesthetic on the one hand, and highly complex contents on the other.