In Silico Modeling and Experimental Validation for Improving Methanogenesis from CO2 Via M. Maripaludis

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Focusing on the metabolic capabilities of M. maripaludis, this thesis investigates its potential to convert CO2 into methane in nitrogen-rich environments. It presents a comprehensive review of the organism's metabolic processes and introduces the first genome-scale metabolic model (iMM518). Notably, it highlights the influence of nitrogen fixation on methane production, making it a valuable resource for researchers in biofuels, systems biology, nitrogen-fixing microbes, and bioremediation.