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Focusing on confirmatory adaptive designs, this book offers a comprehensive review of their principles and techniques, emphasizing their evolution from group sequential designs. It details the process of conducting interim analyses to potentially halt trials while managing Type I error rates. Additionally, the text covers the flexibility of adaptive designs, allowing for data-driven modifications such as reassessing sample sizes, selecting treatment arms, or identifying specific sub-populations during the study.
Buchkauf
Group Sequential and Confirmatory Adaptive Designs in Clinical Trials, Gernot Wassmer, Werner Brannath
- Sprache
- Erscheinungsdatum
- 2016
- product-detail.submit-box.info.binding
- (Hardcover)
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- Titel
- Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
- Sprache
- Englisch
- Autor*innen
- Gernot Wassmer, Werner Brannath
- Erscheinungsdatum
- 2016
- Einband
- Hardcover
- Seitenzahl
- 320
- ISBN13
- 9783319325606
- Kategorie
- Medizin & Gesundheit, Mathematik
- Beschreibung
- Focusing on confirmatory adaptive designs, this book offers a comprehensive review of their principles and techniques, emphasizing their evolution from group sequential designs. It details the process of conducting interim analyses to potentially halt trials while managing Type I error rates. Additionally, the text covers the flexibility of adaptive designs, allowing for data-driven modifications such as reassessing sample sizes, selecting treatment arms, or identifying specific sub-populations during the study.