Bisphosphonates induced osteonecrosis of the jaw

The book delves into BRONJ, a serious condition linked to Bisphosphonate therapy, particularly in patients undergoing long-term nitrogen-containing IV treatments or invasive dental procedures. It emphasizes the necessity of thorough dental evaluations before starting IV BPs to mitigate risks. The text discusses the role of CBCT, serum VEGF levels, and morning fasting CTX as assessment tools for predicting risk and guiding treatment. For those already affected, management strategies focus on palliative and empirical approaches.