Synthesis, Characterization and Biological Evaluation of Anticancer drug

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The book explores the evolution of cancer chemotherapy, marking its origins in 1945 with the discovery of nitrogen mustards for treating leukemias. It details the initial skepticism surrounding cisplatin, which later showed promise in clinical trials for ovarian cancer. The narrative emphasizes the importance of conducting comprehensive phase I and II trials to explore new anticancer agents, driven by advancements in understanding cancer cell biology and its distinctions from normal tissues.