Regulation of Immune Gene Expression

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The proceedings from a 1985 conference at Trinity College, Oxford, focus on the immune response gene workshops aimed at understanding the differences in antibody responses among various experimental animal strains. The research identified immune response (Ir) gene products, particularly la antigens, as crucial to these responses. While significant advancements have been made in defining these proteins and their genetic components, the underlying mechanisms of high and low responsiveness to antigens remain poorly understood, highlighting the complexity of immune regulation.