3' End Choice: Impact on Genes & Disease

The 3' untranslated region (UTR) plays a crucial role in gene expression regulation, acting as a control point that affects protein production levels. This sequence can bind regulatory molecules, influencing mRNA stability and translation. Mutations in the 3' UTR may lead to imbalances in protein synthesis, which are associated with diseases such as cancer and neurodegenerative disorders. By exploring the 3' UTR's function, researchers aim to develop innovative therapies that could correct these imbalances and improve health outcomes.