Liquisolid Technology

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The book explores the innovative liquisolid technique for enhancing the solubility of poorly soluble drugs. By blending liquid formulations with specific excipients, it transforms them into flowing and compressible powders. This method involves saturating a carrier, typically microcrystalline cellulose, with a non-volatile liquid vehicle, which is then coated with fine particles of amorphous silicon dioxide. The result is a dry powder that maintains the benefits of liquid formulations, significantly improving the dissolution rate of medications.