The study focuses on the antioxidant properties of Ocimum citriodurum, revealing that rosmarinic acid is the predominant compound in its hydroalcoholic extract. Utilizing HPLC-MS, researchers identified seven chemical constituents and established an active potential of 0.547 for the extract's antioxidant activity. In vitro tests confirmed its efficacy with a 50% effective concentration of 50.53 mg/L against the DPPH method. Additionally, a Didactic Sequence was developed to teach about bioactive molecules and antioxidants, integrating findings with organic chemistry content.
Victor Elias Mouchrek Filho Reihenfolge der Bücher






- 2023
- 2023
Ixora coccinea L. : extracts and hydroalcoholic fractions
Antioxidant, anti-inflammatory and anti-arthritic potentials
- 52 Seiten
- 2 Lesestunden
The study investigates the chemical and biological properties of Ixora coccinea L. through hydroalcoholic extracts and fractions. Using high-performance liquid chromatography coupled with mass spectrometry (HPLC/MS), catechol was identified as the predominant component. The research assessed antioxidant, anti-inflammatory, and anti-arthritic activities, revealing effective concentrations (EC50) that indicate strong biological activity across all assays. The antioxidant activity showed EC50 values between 6.45 and 87.15 ppm, while anti-inflammatory and anti-arthritic activities ranged from 32.27 to 198.06 ppm and 10.76 to 66.02 ppm, respectively.
- 2023
The study focuses on the antioxidant properties of natural molecules from the hydroalcoholic extract of Ocimum citriodurum, identifying seven chemical constituents, primarily rosmarinic acid. Using HPLC-MS, the extract demonstrated significant antioxidant activity with an in silico active potential of 0.547 and an in vitro EC50 of 50.53 mg/L against the DPPH method. Additionally, the research led to the development of an educational Teaching Sequence on bioactive molecules and antioxidants, integrating Organic Functions into the curriculum through the PASS Online and PubChem resources.
- 2022
The study investigates the larvicidal properties of essential oil and nanoemulsion derived from Coleus aromaticus Benth leaves against Aedes aegypti larvae. It reveals a significant phenolic content and promising antioxidant activity. The essential oil demonstrated larvicidal effects with an LC50 of 3.24 mg L-1, while the nanoemulsion exhibited even greater efficacy at 1.83 mg L-1. These findings suggest the potential of both products as biocontrol agents in combating Aedes aegypti, highlighting the market viability of the nanoemulsion.
- 2021
The research investigates the chemical composition and larvicidal properties of microencapsulated essential oil from Citrus aurantium against Aedes aegypti. Extracted through hydrodistillation, the oil was characterized using GC-MS, revealing key components like (-)-Terpinen-4-ol and Caryophyllene oxide. The study employed the Folin-Ciocalteu method to measure phenolic content and determined the oil's lethality, finding an LC50 of 3.589 mg L-1. The findings suggest the essential oil's effectiveness as a potential agent for controlling mosquito populations.
- 2021
Larvicidal activity against Aedes aegypti larvae
Larvicidal activity against Aedes aegypti essential oil larvae ofAniba rosaeodora Ducke
- 52 Seiten
- 2 Lesestunden
The study investigates the essential oil of Aniba rosaeodora, focusing on its chemical composition, toxicity, antioxidant potential, and effectiveness against Aedes aegypti larvae. Extracted via hydrodistillation, the oil predominantly contains -linalol at 63.16%, highlighting its pharmaceutical promise. Toxicity tests indicate it is non-toxic, while the oil demonstrates significant larvicidal activity with an LC50 of 41.07 mgL-1, along with notable antioxidant properties. These findings suggest its potential application in controlling mosquito populations.
- 2020
Larvicidal activity against Aedes aegypti of Aniba rosaeodora Ducke
Chemical constituents and larvicidal activity against Aedes aegypti larvae of Aniba rosaeodora Ducke
- 52 Seiten
- 2 Lesestunden
The study investigates the essential oil of Aniba rosaeodora Ducke, highlighting its primary chemical component, linalool, which constitutes 63.16% of the oil and shows promise for pharmaceutical applications. Toxicity tests indicate a non-toxic profile, with an LC50 range of 582 to 282 mg L-1. The oil exhibits effective larvicidal activity against Aedes aegypti, with an LC50 of 41.07 mg L-1, and demonstrates significant antioxidant properties. These findings suggest its potential for application in pest control and health-related fields.
- 2020
Ätherische Öle von Hymenaea courbaril und Syzygium cumini
Chemische Charakterisierung, Toxizität, antioxidative und antimikrobielle Aktivität
- 64 Seiten
- 3 Lesestunden
Die Studie beleuchtet die antimikrobielle und antioxidative Wirkung der ätherischen Öle von Hymenaea courbaril und Syzygium cumini. Der Hauptbestandteil des Öls von H. courbaril ist beta-Ozimen, während S. cumini Isocaryophyllen enthält. Beide Öle zeigen eine starke antioxidative Aktivität sowie Toxizität gegenüber Artemia salina. Zudem besitzen sie bakterizide Eigenschaften gegen mehrere pathogene Bakterien, darunter E. coli und S. aureus. Die Ergebnisse deuten auf das Potenzial dieser ätherischen Öle zur Bekämpfung von Mikroorganismen hin.
- 2020
Essential oils against mollusks Biomphalaria glabrata
Using essential oils used by hydrodistillation to assess the mortality of schistosomiasis-transmitting snails
- 52 Seiten
- 2 Lesestunden
The study investigates the molluscicidal properties of essential oils from Syzygium cumini and Hymenaea courbaril, extracted through hydrodistillation and analyzed via Gas Chromatography-Mass Spectrometry. Toxicity tests using Artemia salina indicated both oils were nontoxic, with specific LC50 values for each. The molluscicidal assays revealed effective concentrations against Biomphalaria glabrata, suggesting these essential oils could serve as natural alternatives to combat schistosomiasis-carrying snails.
- 2020
Influence of drying on the essential oil of Alpinia zerumbet leaves
Mathematical modelling of Alpinia zerumbet leaves and biological properties of its essential oils
- 52 Seiten
- 2 Lesestunden
The study investigates the impact of drying Alpinia leaves on the properties of their essential oils, utilizing mathematical models to analyze the drying process. Results indicate significant variations in essential oil characteristics based on drying conditions, with 45 °C yielding optimal antimicrobial activity and lower toxicity. The findings highlight the importance of drying temperature in affecting the physicochemical and biological properties of essential oils, underscoring the need for further research to refine predictive models for drying processes.