From Molecules to Networks

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An understanding of the nervous system at any level necessitates knowledge of its fundamental unit, the neuron. The third edition of this text offers a comprehensive foundation in the morphological, biochemical, and biophysical properties of nerve cells. It retains the focus on cellular and molecular neurobiology and computational neuroscience, while also enhancing it. Each chapter has been thoroughly revised to incorporate significant advances from the past five years. This edition expands on the network aspects of cellular neurobiology, introducing new coverage of specific research methods such as patch-clamp electrophysiology, ligand binding, and structural techniques like x-ray crystallography. Authored by leading experts, it updates all chapters to reflect the latest primary research findings. Notable features include an introduction to mathematical modeling and simulation approaches, 80% updated and new content, a new chapter on the biophysics of voltage-gated ion channels, a new chapter on synaptic plasticity, and a chapter on the neurobiology of disease. The text is highly referenced, comprehensive, and quantitative, with full-color professional graphics throughout, all available in electronic format for teaching purposes.